A GLOBAL COMPARISON OF THE HUMAN AND T. BRUCEI DEGRADOMES GIVES INSIGHTS ABOUT POSSIBLE PARASITE DRUG TARGETS.

A global comparison of the human and T. brucei degradomes gives insights about possible parasite drug targets.

We performed a genome-level computational study of sequence and structure similarity, the latter using vent right crystal structures and models, of the proteases of Homo sapiens and the human parasite Trypanosoma brucei.Using sequence and structure similarity networks to summarize the results, we constructed global views that show visually the rela

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Tissue-engineered rhesus monkey nerve grafts for the repair of long ulnar nerve defects: similar outcomes to autologous nerve grafts

Acellular nerve allografts can help preserve normal nerve structure and extracellular matrix composition.These allografts have low immunogenicity and are more readily available than autologous nerves for the repair of long-segment peripheral nerve defects.In this study, we repaired a 40-mm ulnar nerve defect in rhesus monkeys with tissue-engineered

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